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Researchers at Brown University have unlocked the method genetic mutations use to disrupt communication between neurons and muscles in spinal muscular atrophy, or SMA.

SMA is incurable and fatal in early childhood in its most severe form, but the first treatment for the disease was approved for use by the Food and Drug Administration in December 2016.

If your neurological disorder results in only mental impairment or if you have a co-occurring mental condition that is not caused by your neurological disorder (for example, dementia), we will evaluate your mental impairment under the mental disorders body system, 12.00. In 11.02 (Epilepsy), 11.06 (Parkinsonian syndrome), and 11.12 (Myasthenia gravis), we require that limitations from these neurological disorders exist despite adherence to prescribed treatment.

“Despite adherence to prescribed treatment” means that you have taken medication(s) or followed other treatment procedures for your neurological disorder(s) as prescribed by a physician for three consecutive months but your impairment continues to meet the other listing requirements despite this treatment.

You may receive your treatment at a health care facility that you visit regularly, even if you do not see the same physician on each visit. We must have a description of a recent comprehensive evaluation including all areas of communication, performed by an acceptable medical source, to document a communication impairment associated with a neurological disorder.

A communication impairment may occur when a medically determinable neurological impairment results in dysfunction in the parts of the brain responsible for speech and language.I have had an SPC for 16 years now and it has mostly been super.There is not much first hand info on the net so I will share my personal experience.In order to account for these differences, the chromosome 5 SMA often is classified into types 1 through 4.The age at which SMA symptoms begin roughly correlates with the degree to which motor function is affected: The earlier the age of onset, the greater the impact on motor function.The first breakthrough in the disease came in the form of spinal cord injections of the newly approved drug nusinersen, which restores some motor function and prolongs life.

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